Hitesh Sharma Selected Research

thymidylate synthase-dihydrofolate reductase

2/2014	Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase.
10/2013	First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling.
9/2013	Selective peptide inhibitors of bifunctional thymidylate synthase-dihydrofolate reductase from Toxoplasma gondii provide insights into domain-domain communication and allosteric regulation.

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Hitesh Sharma Research Topics

Disease

2	Abscess 12/2016 - 12/2016
2	Ulcer 12/2016 - 12/2016
2	Infections 02/2014 - 10/2013
1	Neoplasms (Cancer) 05/2022
1	Carcinoma (Carcinomatosis) 01/2021
1	Pulmonary Tuberculosis 01/2018
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2016
1	Uveomeningoencephalitic Syndrome (Vogt Koyanagi Harada Syndrome) 12/2016
1	Parasitic Diseases (Parasitic Disease) 10/2013
1	Opportunistic Infections (Opportunistic Infection) 10/2013
1	Toxoplasmosis 09/2013
1	Hyperuricemia 12/2011
1	Gout 12/2011

Drug/Important Bio-Agent (IBA)

3	thymidylate synthase-dihydrofolate reductaseIBA 02/2014 - 09/2013
2	Anti-Bacterial Agents (Antibiotics)IBA 12/2016 - 12/2016
2	Pharmaceutical PreparationsIBA 02/2014 - 10/2013
2	EnzymesIBA 02/2014 - 10/2013
1	AutoantibodiesIBA 05/2022
1	Endoplasmic Reticulum Chaperone BiPIBA 05/2022
1	Tuberculin (PPD)IBA 01/2018
1	Amphotericin B (Amphotericin)FDA LinkGeneric 12/2016
1	Natamycin (Pimaricin)FDA Link 12/2016
1	SteroidsIBA 12/2016
1	NucleotidesIBA 02/2014
1	Antiparasitic Agents (Antiparasitics)IBA 10/2013
1	Thymidylate SynthaseIBA 10/2013
1	Febuxostat FDA Link 12/2011

Therapy/Procedure

3	Therapeutics 05/2022 - 12/2016
1	Radiotherapy 01/2021
1	Drug Therapy (Chemotherapy) 12/2016